“Layla” by Derek and The Dominos

Layla by Derek and The Dominos definitely deserves a spot on this list. Eric Clapton is not a one-hit-wonder, however, this song from the band Derek and the Dominos was. This single was a part of an album with the title Layla and Other Assorted Love Songs. This song was written based on Clapton’s unrequited feelings for a woman that was the wife of the Beatles George Harrison, which came as a shock to people who found this out.